Associations of insulin and insulin-like growth factors with physical performance in old age in the Boyd Orr and Caerphilly studies.

Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition. We hypothesised that IGF-I and IGF-II are associated with improved, and insulin with worse, physical performance in old age.Physical performance was mea...

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Bibliographic Details
Main Authors: Kate Birnie, Yoav Ben-Shlomo, Jeff M P Holly, David Gunnell, Shah Ebrahim, Antony Bayer, John Gallacher, Richard M Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3254635?pdf=render