Engineering strong and stress-responsive promoters in Bacillus subtilis by interlocking sigma factor binding motifs

Prokaryotic gene expression is largely regulated on transcriptional levels with the involvement of promoters, RNA polymerase and sigma factors. Developing new promoters to customize gene transcriptional regulation becomes increasingly demanded in synthetic biology and biotechnology. In this study, w...

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Bibliographic Details
Main Authors: Yang Wang, Yanan Shi, Litao Hu, Guocheng Du, Jian Chen, Zhen Kang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-12-01
Series:Synthetic and Systems Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X19300420