Prognostic role of MUC5B rs35705950 genotype in patients with idiopathic pulmonary fibrosis (IPF) on antifibrotic treatment

Prognostic role of MUC5B rs35705950 genotype in patients with idiopathic pulmonary fibrosis (IPF) on antifibrotic treatment

Abstract Background A common variant located in the promoter region of MUC5B (rs35705950) is the strongest risk factor for sporadic and familiar IPF, as well as a predictor of outcome. However, there are no data on the effect of MUC5B rs35705950 genotype on the prognosis of IPF patients on antifibro...

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Bibliographic Details
Main Authors: Davide Biondini, Elisabetta Cocconcelli, Nicol Bernardinello, Giulia Lorenzoni, Chiara Rigobello, Sara Lococo, Gioele Castelli, Simonetta Baraldo, Manuel G. Cosio, Dario Gregori, Marina Saetta, Elisabetta Balestro, Paolo Spagnolo
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Respiratory Research
Subjects:
Genetics
Idiopathic pulmonary fibrosis
Interstitial lung diseases
MUC5B
Polymorphisms
Online Access:https://doi.org/10.1186/s12931-021-01694-z

Internet

https://doi.org/10.1186/s12931-021-01694-z

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