Unraveling the mechanism of the cadherin-catenin-actin catch bond.
The adherens junctions between epithelial cells involve a protein complex formed by E-cadherin, β-catenin, α-catenin and F-actin. The stability of this complex was a puzzle for many years, since in vitro studies could reconstitute various stable subsets of the individual proteins, but never the enti...
Main Authors: | Shishir Adhikari, Jacob Moran, Christopher Weddle, Michael Hinczewski |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-08-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC6114904?pdf=render |
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