A novel synthesis of 2,5-di-substituted pyridine derivatives by the ring opening and closing cascade (ROCC) mechanism

A new regioselective method for the synthesis of 2-aryl-5-benzoylpyridine derivatives has been developed. The reaction proceeds via ring opening and closing cascade mechanism (ROCC) of isoxazole to synthesize various functionalized pyridine derivatives. This is the first report for the preparation o...

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Bibliographic Details
Main Authors: K. Raghavulu, M. Sambaiah, Ramakrishna Gudipati, K. Basavaiah, Satyanarayana Yennam, Manoranjan Behera
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Journal of Saudi Chemical Society
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610319300559