Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling

Abstract Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic disease, which causes high fever, thrombocytopenia, and death in humans and animals in East Asian countries. The pathogenicity of SFTS virus (SFTSV) remains unclear. We intraperitoneally infected three groups of mice...

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Main Authors: Seok-Chan Park, Jun Young Park, Jin Young Choi, Sung-Geun Lee, Seong Kug Eo, Jae-Ku Oem, Dong-Seob Tark, Myungjo You, Do-Hyeon Yu, Joon-Seok Chae, Bumseok Kim
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Laboratory Animal Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42826-020-00070-0