A Hybrid Approach for CpG Island Detection in the Human Genome.

BACKGROUND:CpG islands have been demonstrated to influence local chromatin structures and simplify the regulation of gene activity. However, the accurate and rapid determination of CpG islands for whole DNA sequences remains experimentally and computationally challenging. METHODOLOGY/PRINCIPAL FINDI...

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Bibliographic Details
Main Authors: Cheng-Hong Yang, Yu-Da Lin, Yi-Cheng Chiang, Li-Yeh Chuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4705099?pdf=render