α-Amylase and dipeptidyl peptidase-4 (DPP-4) inhibitory effects of Melicope latifolia bark extracts and identification of bioactive constituents using in vitro and in silico approaches

α-Amylase and dipeptidyl peptidase-4 (DPP-4) inhibitory effects of Melicope latifolia bark extracts and identification of bioactive constituents using in vitro and in silico approaches

Context Melicope latifolia (DC.) T. G. Hartley (Rutaceae) was reported to contain various phytochemicals including coumarins, flavonoids, and acetophenones. Objective This study investigates the antidiabetic and antioxidant effects of M. latifolia bark extracts, fractions, and isolated constituents....

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Bibliographic Details
Main Authors: Alexandra Quek, Nur Kartinee Kassim, Pei Cee Lim, Dai Chuan Tan, Muhammad Alif Mohammad Latif, Amin Ismail, Khozirah Shaari, Khalijah Awang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
diabetes
antidiabetic
molecular docking
antioxidant
Online Access:http://dx.doi.org/10.1080/13880209.2021.1948065

Internet

http://dx.doi.org/10.1080/13880209.2021.1948065

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