FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR

FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR

Abstract Background Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been linked to tumor progression in many types of cancer. The role of FGFR3 in melanoma remains unclear. In this study, we aimed to uncover the role of FGFR3 in the growth and metastasis of melanoma. Methods FGFR3...

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Bibliographic Details
Main Authors: Lei Li, Shuai Zhang, Hao Li, Haiyan Chou
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Subjects:
FGFR3
Melanoma
Metastasis
Epithelial-mesenchymal transition
ERK
AKT
Online Access:http://link.springer.com/article/10.1186/s12885-019-6161-8

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http://link.springer.com/article/10.1186/s12885-019-6161-8

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