Optimized Extraction of Amikacin from Murine Whole Blood

Optimized Extraction of Amikacin from Murine Whole Blood

Amikacin (Amk) analysis and quantitation, for pharmacokinetics studies and other types of investigations, is conventionally performed after extraction from plasma. No report exists so far regarding drug extraction from whole blood (WB). This can represent an issue since quantification in plasma does...

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Bibliographic Details
Main Authors: Roccaldo Sardella, Styliani Xiroudaki, Laura Mercolini, Samuele Sabbatini, Claudia Monari, Stefano Perito, Federica Ianni, Anna Vecchiarelli, Stefano Giovagnoli
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
pharmaco-toxicological investigation
sample derivatization
screening of extraction conditions
Online Access:https://www.mdpi.com/1420-3049/26/3/665

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https://www.mdpi.com/1420-3049/26/3/665

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