The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina

Summary: Notch signaling in neural progenitor cell is triggered by ligands expressed in adjacent cells. To identify the sources of active Notch ligands in the mouse retina, we negatively regulated Notch ligand activity in various neighbors of retinal progenitor cells (RPCs) by eliminating mindbomb E...

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Bibliographic Details
Main Authors: Taejeong Ha, Kyeong Hwan Moon, Le Dai, Jun Hatakeyama, Keejung Yoon, Hee-Sae Park, Young-Yoon Kong, Kenji Shimamura, Jin Woo Kim
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717303868