Cytosine hydroxymethylation by TET enzymes: From the control of gene expression to the regulation of DNA repair mechanisms, and back

Chromatin is a complex multi-scale structure composed of DNA wrapped around nucleosomes. The compaction state is finely regulated mainly by epigenetic marks present not only on nucleosomes but also on the DNA itself. The most studied DNA post-transcriptional modification is 5-methylcytosine (5-mC)....

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Bibliographic Details
Main Authors: Audrey Lejart, Gilles Salbert, Sébastien Huet
Format: Article
Language:English
Published: AIMS Press 2018-09-01
Series:AIMS Biophysics
Subjects:
Online Access:http://www.aimspress.com/biophysics/article/3104/fulltext.html