ENVIRONMENTAL ENRICHMENT STRENGTHENS CORTICOCORTICAL INTERACTIONS AND REDUCES AMYLOID-β OLIGOMERS IN AGED MICE
Brain aging is characterized by global changes which are thought to underlie age-related cognitive decline. These include variations in brain activity and the progressive increase in the concentration of soluble amyloid-β (Aβ) oligomers, directly impairing synaptic function and plasticity even in th...
Main Authors: | Marco eMainardi, Angelo eDi Garbo, Matteo eCaleo, Nicoletta eBerardi, Alessandro eSale, Lamberto eMaffei |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-01-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00001/full |
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