ENVIRONMENTAL ENRICHMENT STRENGTHENS CORTICOCORTICAL INTERACTIONS AND REDUCES AMYLOID-β OLIGOMERS IN AGED MICE

ENVIRONMENTAL ENRICHMENT STRENGTHENS CORTICOCORTICAL INTERACTIONS AND REDUCES AMYLOID-β OLIGOMERS IN AGED MICE

Brain aging is characterized by global changes which are thought to underlie age-related cognitive decline. These include variations in brain activity and the progressive increase in the concentration of soluble amyloid-β (Aβ) oligomers, directly impairing synaptic function and plasticity even in th...

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Bibliographic Details
Main Authors: Marco eMainardi, Angelo eDi Garbo, Matteo eCaleo, Nicoletta eBerardi, Alessandro eSale, Lamberto eMaffei
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Aging
Neprilysin
EEG
environmental enrichment
cross-correlation
VGAT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00001/full

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