Ocular Pharmacological Profile of Hydrocortisone in Dry Eye Disease

Ocular Pharmacological Profile of Hydrocortisone in Dry Eye Disease

To investigate the ocular pharmacological profile of hydrocortisone (HC) using in vitro and in vivo models of dry eye disease. Rabbit corneal epithelial cells (SIRCs) were used to assess the effect of HC in two paradigms of corneal damage: hyperosmotic stress and scratch-wound assay. Dry eye was ind...

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Bibliographic Details
Main Authors: Claudio Bucolo, Annamaria Fidilio, Claudia Giuseppina Fresta, Francesca Lazzara, Chiara Bianca Maria Platania, Giuseppina Cantarella, Giulia Di Benedetto, Chiara Burgaletto, Renato Bernardini, Cateno Piazza, Stefano Barabino, Filippo Drago
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
dry eye disease
inflammation
cornea
hydrocortisone
Sjögren syndrome
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01240/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01240/full

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