Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy

Radiotherapy exerts part of its antineoplastic effect by generating oxidative stress, therefore genetic variation in oxidative stress-related enzymes may influence survival of rectal cancer patients. We hypothesized that genetic polymorphisms associated with higher amounts of reactive oxygen specie...

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Bibliographic Details
Main Authors: Silvia Funke, Angela Risch, Alexandra Nieters, Michael Hoffmeister, Christa Stegmaier, Christoph M. Seiler, Hermann Brenner, Jenny Chang-Claude
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Cancer Epidemiology
Online Access:http://dx.doi.org/10.1155/2009/302047