Curcumin improves necrotising microscopic colitis and cell pyroptosis by activating SIRT1/NRF2 and inhibiting the TLR4 signalling pathway in newborn rats

This study aimed to explore comprehensively the biological function of curcumin, and its underlying mechanism, in protecting from necrotising microscopic colitis in newborn rats. A total of 20 normal healthy rats were selected, and a necrotising enterocolitis (NEC) model was established. After hypox...

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Bibliographic Details
Main Authors: Yiyu Yin, Xiaole Wu, Bei Peng, Huaxin Zou, Shixian Li, Jian Wang, Junhua Cao
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425920933656