Laser scanning reflection-matrix microscopy for aberration-free imaging through intact mouse skull

Microscopic imaging of the brain usually requires thinning of the skull, as it causes complex aberration. Here, the authors introduce a label-free imaging modality termed laser scanning reflection-matrix microscopy, which allows for correcting these aberrations and in vivo imaging through an intact...

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Bibliographic Details
Main Authors: Seokchan Yoon, Hojun Lee, Jin Hee Hong, Yong-Sik Lim, Wonshik Choi
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19550-x