Astrocytic gap junction inhibition by carbenoxolone enhances the protective effects of ischemic preconditioning following cerebral ischemia

Astrocytic gap junction inhibition by carbenoxolone enhances the protective effects of ischemic preconditioning following cerebral ischemia

Abstract Background Stroke is the second leading cause of death worldwide and the most common cause of adult-acquired disability in many nations. Thus, attenuating the damage after ischemic injury and improving patient prognosis are of great importance. We have indicated that ischemic preconditionin...

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Bibliographic Details
Main Authors: Di Ma, Liangshu Feng, Yingying Cheng, Meiying Xin, Jiulin You, Xiang Yin, Yulei Hao, Li Cui, Jiachun Feng
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Neuroinflammation
Subjects:
Cerebral ischemic preconditioning
Ischemia reperfusion
Reactive oxygen species
Oxygen-glucose deprivation
Gap junction
Connexin 43
Online Access:http://link.springer.com/article/10.1186/s12974-018-1230-5

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http://link.springer.com/article/10.1186/s12974-018-1230-5

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