Hypogonadism in thalassemia major patients

Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients. Hypogonadism, mostly hypogonadotropic hypogonadism, is usually detected during puberty. Early diagnosis and treatment are crucial for n...

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Bibliographic Details
Main Authors: Sasima Srisukh, Boonsong Ongphiphadhanakul, Pongamorn Bunnag
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Clinical & Translational Endocrinology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214623716300205