Design of multi-specificity in protein interfaces.
Interactions in protein networks may place constraints on protein interface sequences to maintain correct and avoid unwanted interactions. Here we describe a "multi-constraint" protein design protocol to predict sequences optimized for multiple criteria, such as maintaining sets of interac...
Main Authors: | Elisabeth L Humphris, Tanja Kortemme |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-08-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.0030164 |
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