Targeted Isolation of Tsitsikammamines from the Antarctic Deep-Sea Sponge Latrunculia biformis by Molecular Networking and Anticancer Activity

Targeted Isolation of Tsitsikammamines from the Antarctic Deep-Sea Sponge Latrunculia biformis by Molecular Networking and Anticancer Activity

The Antarctic deep-sea sponge Latrunculia (Latrunculia) biformis Kirkpatrick, 1908 (Class Demospongiae Sollas, Order Poecilosclerida Topsent, Latrunculiidae Topsent) was selected for chemical analyses due to its potent anticancer activity. Metabolomic analysis of its crude extract by HRMS/MS-based m...

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Bibliographic Details
Main Authors: Fengjie Li, Dorte Janussen, Christian Peifer, Ignacio Pérez-Victoria, Deniz Tasdemir
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Marine Drugs
Subjects:
Antarctica
deep-sea
marine sponge
Latrunculia
molecular networking
molecular docking
tsitsikammamine
Online Access:http://www.mdpi.com/1660-3397/16/8/268

Internet

http://www.mdpi.com/1660-3397/16/8/268

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