Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers.

<h4>Background</h4>Cancer Associated Fibroblasts (CAFs) are thought to regulate tumor growth and metastasis. Fibroblast Activating Protein 1 (FAP-1) is a marker for fibroblast activation and by many recognized as the main marker of CAFs. Alpha Smooth Muscle Actin (α-SMA) is a general myo...

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Main Authors: Thomas K Kilvaer, Mehrdad Rakaee Khanehkenari, Turid Hellevik, Samer Al-Saad, Erna-Elise Paulsen, Roy M Bremnes, Lill-Tove Busund, Tom Donnem, Inigo Z Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0134965