The eroding chromatin landscape of aging stem cells
Adult stem cells undergo both replicative and chronological aging in their niches, with catastrophic declines in regenerative potential with age. Due to repeated environmental insults during aging, the chromatin landscape of stem cells erodes, with changes in both DNA and histone modifications, accu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2020-01-01
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| Series: | Translational Medicine of Aging |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468501120300195 |