The effect of TIP on pneumovirus-induced pulmonary edema in mice.

BACKGROUND:Pulmonary edema plays a pivotal role in the pathophysiology of respiratory syncytial virus (RSV)-induced respiratory failure. In this study we determined whether treatment with TIP (AP301), a synthetic cyclic peptide that mimics the lectin-like domain of human TNF, decreases pulmonary ede...

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Bibliographic Details
Main Authors: Elske van den Berg, Reinout A Bem, Albert P Bos, Rene Lutter, Job B M van Woensel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105480?pdf=render