Circ_0001721 enhances doxorubicin resistance and promotes tumorigenesis in osteosarcoma through miR-758/TCF4 axis

Circ_0001721 enhances doxorubicin resistance and promotes tumorigenesis in osteosarcoma through miR-758/TCF4 axis

Abstract Background Osteosarcoma (OS) is a common type of bone malignancy that often occurs in children and adolescents. Chemoresistance is a huge barrier to cancer therapy. This study aimed to investigate the role and potential mechanism of circ_0001721 in doxorubicin (DXR) resistance and OS develo...

Full description

Bibliographic Details
Main Authors: Huapeng Guan, Hao Xu, Jinshui Chen, Weishan Wu, Dongfeng Chen, Yungang Chen, Jianzhong Sun
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cancer Cell International
Subjects:
Osteosarcoma
circ_0001721
miR-758
TCF4
Doxorubicin
Tumorigenesis
Online Access:https://doi.org/10.1186/s12935-021-02016-5

Internet

https://doi.org/10.1186/s12935-021-02016-5

Similar Items