Oxysophocarpine Retards the Growth and Metastasis of Oral Squamous Cell Carcinoma by Targeting the Nrf2/HO-1 Axis

Oxysophocarpine Retards the Growth and Metastasis of Oral Squamous Cell Carcinoma by Targeting the Nrf2/HO-1 Axis

Background/Aims: Nuclear factor erythroid 2-related factor 2 (Nrf2) is an oncogene in various types of cancers, including oral squamous cell carcinoma (OSCC). Oxysophocarpine (OSC) is a natural alkaloid that has multiple pharmacological activities. However, the biological functions and molecular mec...

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Bibliographic Details
Main Authors: Rui Liu, Jia Peng, Huili Wang, Lei Li, Xiujie Wen, Yan Tan, Lin Zhang, Haoyuan Wan, Faming Chen, Xie Nie
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oral squamous cell carcinoma
Growth
Metastasis
Oxysophocarpine
Nrf2
HO-1
Online Access:https://www.karger.com/Article/FullText/493615

Internet

https://www.karger.com/Article/FullText/493615

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