The Antioxidant Procyanidin Reduces Reactive Oxygen Species Signaling in Macrophages and Ameliorates Experimental Colitis in Mice

The Antioxidant Procyanidin Reduces Reactive Oxygen Species Signaling in Macrophages and Ameliorates Experimental Colitis in Mice

Management of inflammatory bowel disease (IBD) is a real clinical challenge. Despite intense investigation, the mechanisms of IBD remain substantially unidentified. Some inflammatory conditions, such as matrix metalloproteinases (MMPs) and the nuclear factor-κB (NF-κB) and NOD-like receptor protein...

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Bibliographic Details
Main Authors: Lu Chen, Qian You, Liang Hu, Jian Gao, Qianqian Meng, Wentao Liu, Xuefeng Wu, Qiang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
procyanidin
inflammatory bowel disease
reactive oxygen species signaling
MMP9
NF-κB
NLRP3 inflammasome
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01910/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01910/full

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