SomatoSim: precision simulation of somatic single nucleotide variants

Abstract Background Somatic single nucleotide variants have gained increased attention because of their role in cancer development and the widespread use of high-throughput sequencing techniques. The necessity to accurately identify these variants in sequencing data has led to a proliferation of som...

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Bibliographic Details
Main Authors: Marwan A. Hawari, Celine S. Hong, Leslie G. Biesecker
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Bioinformatics
Subjects:
SNV
Online Access:https://doi.org/10.1186/s12859-021-04024-8