Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection

<p>Abstract</p> <p>Background</p> <p>In principle, the elimination of malignancies by oncolytic virotherapy could proceed by different mechanisms - e.g. tumor cell specific oncolysis, destruction of the tumor vasculature or an anti-tumoral immunological response. In thi...

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Bibliographic Details
Main Authors: Yu Yong A, Raab Viktoria, Weibel Stephanie, Worschech Andrea, Wang Ena, Marincola Francesco M, Szalay Aladar A
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/68