Activation of VCAM-1 and Its Associated Molecule CD44 Leads to Increased Malignant Potential of Breast Cancer Cells

VCAM-1 (CD106), a transmembrane glycoprotein, was first reported to play an important role in leukocyte adhesion, leukocyte transendothelial migration and cell activation by binding to integrin VLA-1 (α4β1). In the present study, we observed that VCAM-1 expression can be induced in many breast cance...

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Bibliographic Details
Main Authors: Pei-Chen Wang, Ching-Chieh Weng, You-Syuan Hou, Shu-Fang Jian, Kuan-Te Fang, Ming-Feng Hou, Kuang-Hung Cheng
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:International Journal of Molecular Sciences
Subjects:
EMT
Online Access:http://www.mdpi.com/1422-0067/15/3/3560