The Role of Orphanin FQ/Nociceptin in Neuroplasticity: Relationship to Stress, Anxiety and Neuroinflammation

The neuropeptide, orphanin FQ/nociceptin (OFQ/N or simply, nociceptin), is expressed in both neuronal and nonneuronaltissue, including the immune system. In the brain, OFQ/N has been investigated in relation to stress, anxiety,learning and memory, and addiction. More recently, it has also been found...

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Bibliographic Details
Main Authors: Elyse M Mallimo, Alexander W Kusnecov
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00173/full