Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers

Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers

Abstract Background ADAMs (a disintegrin and metalloproteinase) have long been associated with tumor progression. Recent findings indicate that members of the closely related ADAMTS (ADAMs with thrombospondin motifs) family are also critically involved in carcinogenesis. Gene silencing through DNA m...

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Bibliographic Details
Main Authors: Felix Kordowski, Julia Kolarova, Clemens Schafmayer, Stephan Buch, Torsten Goldmann, Sebastian Marwitz, Christian Kugler, Swetlana Scheufele, Volker Gassling, Christopher G. Németh, Mario Brosch, Jochen Hampe, Ralph Lucius, Christian Röder, Holger Kalthoff, Reiner Siebert, Ole Ammerpohl, Karina Reiss
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Cancer
Subjects:
Colorectal cancer
ADAMTS16
DNA methylation
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12885-018-4701-2

Internet

http://link.springer.com/article/10.1186/s12885-018-4701-2

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