Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer

Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer

A scorpion peptide reported to exhibit both analgesic and antitumor activity in animal models may present as an alternative therapeutic agent for breast cancer. We aimed to investigate the effect of Buthus martensii Karsch antitumor-analgesic peptide (BmK AGAP) on breast cancer cell stemness and epi...

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Bibliographic Details
Main Authors: Sylvanus Kampo, Bulbul Ahmmed, Tingting Zhou, Lawrence Owusu, Thomas Winsum Anabah, Natacha Raissa Doudou, Eugene Dogkotenge Kuugbee, Yong Cui, Zhili Lu, Qiu Yan, Qing-Ping Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
scorpion venom analgesic peptide
rBmK AGAP
stemness
epithelial-mesenchymal transition
pentraxin 3
Wnt/β-catenin signaling
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00021/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00021/full

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