Clinical pharmacogenetics of antiaggregants: clinical pharmacologist' point of view

The review is devoted to individual antiaggregant sensitivity issue. According to numerous studies' data, acetylsalicylic acid is ineffective in 5 % of the patients. It might be explained by target molecule (COG-1) gene polymorphism. This phenomenon has important clinical implications, as aspir...

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Bibliographic Details
Main Authors: D. A. Syche, A. V. Zyatenkov, B. G. Kukes
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2007-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2207