Hec1/Ndc80 Tail Domain Function at the Kinetochore-Microtubule Interface

Successful mitotic cell division is critically dependent on the formation of correct attachments between chromosomes and spindle microtubules. Microtubule attachments are mediated by kinetochores, which are large proteinaceous structures assembled on centromeric chromatin of mitotic chromosomes. The...

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Bibliographic Details
Main Authors: Robert T. Wimbish, Jennifer G. DeLuca
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00043/full