Diabetes mellitus is associated with elevated urinary pyrrole markers of γ-diketones known to cause axonal neuropathy
Introduction Progressive distal symmetrical axonal neuropathy, a complication of diabetes mellitus (DM), has an unknown cause. Normal physiological metabolism and diabetic dysmetabolism are associated with the generation of γ-diketones. γ-Diketones form pyrroles with protein amines, notably with axo...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-04-01
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Series: | BMJ Open Diabetes Research & Care |
Online Access: | https://drc.bmj.com/content/8/1/e001575.full |