Scoring function to predict solubility mutagenesis

<p>Abstract</p> <p>Background</p> <p>Mutagenesis is commonly used to engineer proteins with desirable properties not present in the wild type (WT) protein, such as increased or decreased stability, reactivity, or solubility. Experimentalists often have to choose a small...

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Bibliographic Details
Main Authors: Deutsch Christopher, Tian Ye, Krishnamoorthy Bala
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Algorithms for Molecular Biology
Online Access:http://www.almob.org/content/5/1/33