Necrostatin-1 protection of dopaminergic neurons

Necrostatin-1 protection of dopaminergic neurons

Necroptosis is characterized by programmed necrotic cell death and autophagic activation and might be involved in the death process of dopaminergic neurons in Parkinson′s disease. We hypothesized that necrostatin-1 could block necroptosis and give protection to dopaminergic neurons. There is likely...

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Bibliographic Details
Main Authors: Jing-ru Wu, Jie Wang, Sheng-kui Zhou, Long Yang, Jia-le Yin, Jun-ping Cao, Yan-bo Cheng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; neurodegeneration; necrostatin-1; necroptosis; apoptosis; cytotoxicity; 6-hydroxydopamine; Parkinson′s disease; neuroprotection; autophagy; necrosis; programmed cell death; neurodegenerative disease; PC12 cells; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=7;spage=1120;epage=1124;aulast=Wu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=7;spage=1120;epage=1124;aulast=Wu

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