Blood‐derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs

Blood‐derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs

Evidence has shown that certain methylation markers derived from blood can mirror corresponding methylation signatures in internal tissues. In the current study, we aimed to investigate two strong epigenetic predictors for life span, derived from blood DNA methylation data, in tissue samples of soli...

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Bibliographic Details
Main Authors: Yan Zhang, Melanie Bewerunge‐Hudler, Matthias Schick, Barbara Burwinkel, Esther Herpel, Michael Hoffmeister, Hermann Brenner
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Molecular Oncology
Subjects:
blood and tissues
cancer
DNA methylation
DNAmPhenoAge
mortality risk score
Online Access:https://doi.org/10.1002/1878-0261.12738

Internet

https://doi.org/10.1002/1878-0261.12738

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