P-cadherin counteracts myosin II-B function: implications in melanoma progression

<p>Abstract</p> <p>Background</p> <p>Malignant transformation of melanocytes is frequently attended by a switch in cadherin expression profile as shown for E- and N-cadherin. For P-cadherin, downregulation in metastasizing melanoma has been demonstrated, and over-expres...

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Bibliographic Details
Main Authors: De Wever Olivier, Vanhoecke Barbara, Forsyth Ramses, Brochez Lieve, Van Gele Mireille, Jacobs Koen, Bracke Marc
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/255