Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

Abstract Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopi...

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Main Authors:	Li Liu, Jun-Jie Han, Tian-Shun Xu, Rui-Xing Liu, Li Bao, Hong-Wei Liu
Format:	Article
Language:	English
Published:	SpringerOpen 2018-05-01
Series:	Natural Products and Bioprospecting
Subjects:	Lentinellus ursinus Heptelidic acid derivatives Biosynthetic pathway
Online Access:	http://link.springer.com/article/10.1007/s13659-018-0168-8

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spelling	doaj-3522398c0ccd40f4a8be643a221ec0e62020-11-25T00:29:19ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092018-05-018535536010.1007/s13659-018-0168-8Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinusLi Liu0Jun-Jie Han1Tian-Shun Xu2Rui-Xing Liu3Li Bao4Hong-Wei Liu5State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of SciencesState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of SciencesCollege of Life Sciences, Hebei UniversityState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of SciencesState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of SciencesState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of SciencesAbstract Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1–5 was postulated. Compounds 1–5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. Graphical Abstracthttp://link.springer.com/article/10.1007/s13659-018-0168-8Lentinellus ursinusHeptelidic acid derivativesBiosynthetic pathway
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Li Liu Jun-Jie Han Tian-Shun Xu Rui-Xing Liu Li Bao Hong-Wei Liu
spellingShingle	Li Liu Jun-Jie Han Tian-Shun Xu Rui-Xing Liu Li Bao Hong-Wei Liu Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus Natural Products and Bioprospecting Lentinellus ursinus Heptelidic acid derivatives Biosynthetic pathway
author_facet	Li Liu Jun-Jie Han Tian-Shun Xu Rui-Xing Liu Li Bao Hong-Wei Liu
author_sort	Li Liu
title	Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_short	Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_full	Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_fullStr	Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_full_unstemmed	Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_sort	three new heptelidic acid derivatives from the culture of mushroom lentinellus ursinus
publisher	SpringerOpen
series	Natural Products and Bioprospecting
issn	2192-2195 2192-2209
publishDate	2018-05-01
description	Abstract Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1–5 was postulated. Compounds 1–5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. Graphical Abstract
topic	Lentinellus ursinus Heptelidic acid derivatives Biosynthetic pathway
url	http://link.springer.com/article/10.1007/s13659-018-0168-8
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Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

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