Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

Abstract Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopi...

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Bibliographic Details
Main Authors: Li Liu, Jun-Jie Han, Tian-Shun Xu, Rui-Xing Liu, Li Bao, Hong-Wei Liu
Format: Article
Language:English
Published: SpringerOpen 2018-05-01
Series:Natural Products and Bioprospecting
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13659-018-0168-8
Description
Summary:Abstract Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1–5 was postulated. Compounds 1–5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. Graphical Abstract
ISSN:2192-2195
2192-2209