Ultrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophages.

A series of ultrashort lipopeptides and lipopeptoids were tested for their ability to induce cytokine production in macrophages. Fourteen compounds were found to strongly induce production of chemokines Groα and IL-8, with a structural bias that was absent from previous antibacterial activity invest...

Full description

Bibliographic Details
Main Authors: Brandon Findlay, Neeloffer Mookherjee, Frank Schweizer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3563528?pdf=render