HER2/neu Oncogene and Sensitivity to the DNA-Interactive Drug Doxorubicin

Breast tumor cells overexpressing the proto-oncogene HER2/neu are known to be less responsive to certain DNA-binding chemotherapeutic agents. The current study specifically investigates the correlation between chemosensitivity to the DNA-binding drug doxorubicin and cellular HER2/neu protein levels...

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Bibliographic Details
Main Authors: Anne Mullin, Bertrand Jean-Claude
Format: Article
Language:English
Published: McGill University 2020-12-01
Series:McGill Journal of Medicine
Subjects:
Online Access:https://mjm.mcgill.ca/article/view/673