IceR improves proteome coverage and data completeness in global and single-cell proteomics

Label-free quantitative proteomics by data dependent acquisition offers high protein identification rates but is often limited by missing values. Here, the authors develop a quantification workflow that substantially reduces missing values while maintaining high identification rates and quantificati...

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Bibliographic Details
Main Authors: Mathias Kalxdorf, Torsten Müller, Oliver Stegle, Jeroen Krijgsveld
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25077-6