Prostaglandin Transporter (PGT/SLCO2A1) Protects the Lung from Bleomycin-Induced Fibrosis.

Prostaglandin Transporter (PGT/SLCO2A1) Protects the Lung from Bleomycin-Induced Fibrosis.

Prostaglandin (PG) E2 exhibits an anti-fibrotic effect in the lung in response to inflammatory reactions and is a high-affinity substrate of PG transporter (SLCO2A1). The present study aimed to evaluate the pathophysiological relevance of SLCO2A1 to bleomycin (BLM)-induced pulmonary fibrosis in mice...

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Bibliographic Details
Main Authors: Takeo Nakanishi, Yoshitaka Hasegawa, Reo Mimura, Tomohiko Wakayama, Yuka Uetoko, Hisakazu Komori, Shin-Ichi Akanuma, Ken-Ichi Hosoya, Ikumi Tamai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414486?pdf=render

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http://europepmc.org/articles/PMC4414486?pdf=render

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