<i>Orf Virus</i>-Based Vaccine Vector D1701-V Induces Strong CD8+ T Cell Response against the Transgene but Not against ORFV-Derived Epitopes

The potency of viral vector-based vaccines depends on their ability to induce strong transgene-specific immune response without triggering anti-vector immunity. Previously, <i>Orf virus</i> (ORFV, <i>Parapoxvirus</i>) strain D1701-V was reported as a novel vector mediating pr...

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Bibliographic Details
Main Authors: Alena Reguzova, Michael Ghosh, Melanie Müller, Hanns-Joachim Rziha, Ralf Amann
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/2/295