Direct modulation of myelin-autoreactive CD4+ and CD8+ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules

Direct modulation of myelin-autoreactive CD4+ and CD8+ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules

Weiya Pei, Xin Wan, Khawar Ali Shahzad, Lei Zhang, Shilong Song, Xiaoxiao Jin, Limin Wang, Chen Zhao, Chuanlai Shen Department of Microbiology and Immunology, Medical School, Southeast University, Nanjing, Jiangsu 210009, China Purpose: Numerous nanomaterials have been reported in the treatment of...

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Bibliographic Details
Main Authors: Pei W, Wan X, Shahzad KA, Zhang L, Song S, Jin X, Wang L, Zhao C, Shen C
Format: Article
Language:English
Published: Dove Medical Press 2018-06-01
Series:International Journal of Nanomedicine
Subjects:
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Autoreactive T cells
Immunotherapy
Myelin oligodendrocyte glycoprotein
Biomimetic nanoparticle
Online Access:https://www.dovepress.com/direct-modulation-of-myelin-autoreactive-cd4-and-cd8-t-cells-in-eae-mi-peer-reviewed-article-IJN

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https://www.dovepress.com/direct-modulation-of-myelin-autoreactive-cd4-and-cd8-t-cells-in-eae-mi-peer-reviewed-article-IJN

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