Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain

Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain

Alzheimer’s disease (AD) is characterized by the presence of neuropathological lesions containing amyloid plaques (APs) and neurofibrillary tangles (NFTs). AD is associated with mitochondrial dysfunctions, neuroinflammation and neurodegeneration in the brain. We have previously demonstrated enhanced...

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Bibliographic Details
Main Authors: Ramasamy Thangavel, Duraisamy Kempuraj, Smita Zaheer, Sudhanshu Raikwar, Mohammad E. Ahmed, Govindhasamy Pushpavathi Selvakumar, Shankar S. Iyer, Asgar Zaheer
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
glia maturation factor
mitochondrial uncoupling protein
inducible nitric oxide
NF-κB
para hippocampal gyrus
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00150/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00150/full

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